Revista SPA

Case report: Oncological surgery of the intraocular presentation of a transmissible venereal tumor in a dog

10.22579/22484817.1057
Published 2024-05-01
Proyectos de aula

Abstract

Transmissible Venereal Tumor (TVT) is a contagious neoplasia with a global presence, transmitted mainly through sexual contact. This disease is characterized by primary lesions on the genitals, but it can also affect extra-genital areas. This report describes the case of a two-and-a-half-year-old male mixed-breed dog that was brought to the Veterinary Clinical Center of the University of Los Llanos due to changes in color and enlargement of its right eye. The owner mentioned that the dog had previously been diagnosed with TVT at another center, where it received treatment. Enucleation of the affected eye was chosen as the surgical intervention, followed by histopathological confirmation of TVT, leading to the initiation of chemotherapeutic treatment with vincristine at a dose of 0.025 mg/kg. After the surgery and chemotherapy sessions, the patient showed a satisfactory recovery.

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Authors

  • Juan Diego Mesa Truque

    University of the Llanos

  • Ingrith Maritza Martínez Alvarado

    University of the Llanos

  • Luz Natalia Pedraza Castillo

    University of the Llanos

References

• Abedin, S. N. (2020). Canine transmissible venereal tumor: A review. Journal of Entomology and Zoology Studies, 8(2), 596-599. https://www.entomoljournal.com/archives/2020/vol8issue2/PartK/8-1-352-475.pdf

• Abeka, Y. T. (2019). Review on canine transmissible venereal tumor (CTVT). Cancer Therapy and Oncology International Journal, 14(4), 1-9. https://doi.org/10.19080/CTOIJ.2019.14.555895

• Bendas, A. J., das Neves Moreto, P., Coxo, A. B., Holguin, P. G., & do Vale Soares, D. (2022). Intra-abdominal transmissible venereal tumor in a dog: A case report. Brazilian Journal of Veterinary Medicine, 44. https://doi.org/10.29374/2527-2179.bjvm001422

• Bulhosa, L. F., Estrela, L. A., da Silva Solcà, M., Gonçalves, G. S., Larangeira, D. F., de Pinho, F. A., & Barrouin, M. S. (2020). Vincristine and ivermectin combination chemotherapy in dogs with natural transmissible venereal tumor of different cyto-morphological patterns: A prospective outcome evaluation. Animal Reproduction Science, 216, 106358. https://doi.org/10.1016/j.anireprosci.2020.106358

• Carbonell, J. M., & Suárez, E. M. (2009). Claves para el diagnóstico precoz del glaucoma. REDVET. Revista Electrónica de Veterinaria, 10(3), 1-14. http://www.redalyc.org/articulo.oa?id=63617318004

• Cingi, C., Yeni, D., Yazici, E., Cine, T. A., & Mehmet, U. (2020). Investigation of transmissible venereal tumor in male dogs by cytological examination. Indian Journal of Animal Research, 54(12), 1544-1548. https://doi.org/10.18805/ijar.B-1220

• Çizmeci, S., & Guler, M. (2018). Transmissible venereal tumour (TVT) in bitches and therapy: A review. Malaysian Journal of Veterinary Research, 9(2), 136-143. https://www.dvs.gov.my/dvs/resources/user_16/MJVR%20Vol9%20No%202/MJVR-V9N2-p136-143.pdf

• Costa, T. S., Paiva, F. N., Manier, B. S., Araújo, D. C., Ribeiro, G. B., & Fernandes, J. I. (2023). Epidemiological, clinical, and therapeutic aspects of canine transmissible venereal tumor in Rio de Janeiro, Brazil (2015-2020). Pesquisa Veterinária Brasileira, 43, e07189. https://doi.org/10.1590/1678-5150-PVB-7189

• Crossley, R., & Ramírez, J. A. (2017). Canine transmissible venereal tumor of atypical presentation. Case report. Revista de la Facultad de Medicina Veterinaria y de Zootecnia, 64(3), 78-90. https://pesquisa.bvsalud.org/portal/resource/pt/biblio-902181

• Den Otter, W., Hack, M., Jacobs, J. J., Tan, J. F., Rozendaal, L., & VAN Moorselaar, R. J. (2015a). Effective treatment of transmissible venereal tumors in dogs with vincristine and IL2. Anticancer Research, 35(6), 3385-3391. https://ar.iiarjournals.org/content/anticanres/35/6/3385.full.pdf

• Den Otter, W., Hack, M., Jacobs, J. J., Tan, J. F., Rozendaal, L., & Van Moorselaar, R. J. (2015b). Treatment of transmissible venereal tumors in dogs with intratumoral interleukin-2 (IL-2): A pilot study. Anticancer Research, 35(2), 713-717. https://pubmed.ncbi.nlm.nih.gov/25667450/

• Dubielzig, R. R. (2016). Tumors of the eye. In Tumors in Domestic Animals (pp. 892-922). https://doi.org/10.1002/9781119181200.ch20

• Duzanski, A., Fêo, H., Montoya, L., Seullner, C., & Rocha, N. (2017). Canine transmissible venereal tumor: Is its biological behavior changing? The Anatomical Record, 300(6), 1009-1010. https://doi.org/10.1002/ar.23527

• Fathi, M., Ashry, M., Ali, K. M., Hassan, A., & Elkarmoty, A. F. (2018). Clinico-Pathological Evaluation and Treatment Outcomes of Canine Transmissible Venereal Tumor Using Three Different Protocols. Pakistan Veterinary Journal, 38(2). https://doi.org/10.29261/pakvetj/2018.044

• Firdose, S., Mallappa, R. B., Annayappa, S., Jayanna, R. G., Kalmath, G. P., Rajashekaraiah, R., & Raju, S. B. (2022). Studies on serum oxidative status and hematobiochemical profile in dogs affected with transmissible venereal tumor (TVT). The Pharma Journal, 11(11). https://www.thepharmajournal.com/archives/2022/vol11issue11S/PartD/S-11-10-226-666.pdf

• Fossum, T. W. (2019). Cirugía en pequeños animales. Elsevier Health Sciences.

• Ganguly, B., Das, U., & Das, A. K. (2016). Canine transmissible venereal tumour: A review. Veterinary and Comparative Oncology, 14(1), 1-12. https://doi.org/10.1111/vco.12060

• Gibson, D. N., Singleton, D. A., Brant, B., Radford, A. D., & Killick, D. R. (2021). Temporospatial distribution and country of origin of canine transmissible venereal tumours in the UK. Veterinary Record, 189(12). https://doi.org/10.1002/vetr.974

• Gritzenco, J. D. G., Cabral, A. P. M., Albuquerque, A. P. L., Goulart, J. D. C., Sanches, F. J., Merlini, N. B., Gasser, B., & Marcusso, P. F. (2022). Atypical Transmissible Venereal Tumor in Dogs. Acta Scientiae Veterinariae, 50. https://doi.org/10.22456/1679-9216.117341

• Hantrakul, S., Klangkaew, N., Kunakornsawat, S., Tansatit, T., Poapolathep, A., Kumagai, S., & Poapolathep, S. (2014). Clinical pharmacokinetics and effects of vincristine sulfate in dogs with transmissible venereal tumor (TVT). Journal of Veterinary Medical Science, 76(12), 1549-1553. https://doi.org/10.1292/jvms.14-0180

• Khanhasykov, S. P., & Tokar, V. V. (2022). Transmissible venereal sarcoma in male dogs. Results of operative and conservative treatment. Retrieved from https://www.elibrary.ru/item.asp?id=49809810

• Komnenou, A. T., Thomas, A. L. N., Kyriazis, A. P., Poutahidis, T., & Papazoglou, L. G. (2015). Ocular manifestations of canine transmissible venereal tumour: A retrospective study of 25 cases in Greece. Veterinary Record, 176(20), 523. https://doi.org/10.1136/vr.102968

• Mehmet, U. (2016). Transmissible venereal tumor: A review. Kocatepe Veterinary Journal, 9(3), 230-235. Retrieved from https://dergipark.org.tr/tr/download/article-file/390130

• Muñoz, D. J., Ramírez, R. M., Duque, A. S., & Correa, V. N. (2019). Eye-related neoplasms in dogs: A retrospective study. Revista Colombiana de Ciencias Pecuarias, 32(4), 298-311. https://doi.org/10.17533/udea.rccp.v32n4a07

• Oliveira, C. M. (2019). Doenças do sistema genital e reprodutor. In M. M. Jericó, J. P. Neto Andrade, & M. M. Kogika (Eds.), Tratado de Medicina Interna de Cães e Gatos (1st ed.). Roca. Retrieved from https://edisciplinas.usp.br/pluginfile.php/5246317/mod_resource/content/1/Tratado%20de%20Medicina%20Interna%20de%20-%20Marcia%20Marques%20Jerico%2C%20Joao%20Ped-ilovepdf-compressed.pdf

• Tokar, D., Galaktionov, V., & Khankhasykov, S. (2022). Some aspects of therapy for transmissive venereal sarcoma with vincristine. In Scientific Research of Students in Solving Actual Problems of the Agro-Industrial Complex (pp. 156-161). Retrieved from https://www.elibrary.ru/item.asp?id=49081859

• Vural, S. A., Haziroglu, R., Vural, M. R., Polat, I. M., & Tunc, A. S. (2018). Detection of progressive and regressive phase and LINE-1 retrotransposon in transfected dogs with transmissible venereal tumor during chemotherapy. Journal of Veterinary Science, 19(5), 620-626. https://doi.org/10.4142/jvs.2018.19.5.620

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